BDBM50073190 CHEMBL3408213::US11471446, Compound DBA-11
SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
InChI Key InChIKey=LBFYQISQYCGDDW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50073190
Affinity DataKi: 9nMAssay Description:Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of CDK8 (unknown origin) assessed as inhibition rateMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:The results presented in Example 3 and in particular the KinomeScan indicate that the activity of DBA-7 in our proliferation assay was due to inhibit...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Binding affinity to His-tagged CDK8 (unknown origin) after 60 mins by FRET based lanthascreen binding assayMore data for this Ligand-Target Pair